Mesotherapy consists of intradermic injections of medications, including homeopathic ones, in certain districts of the body.  With very thin needles small quantities of a medication are injected into the derma corresponding to the skin projection of an organ, or part of an organ, which is affected by a pathological process.

Since absorption of a medication at dermic level is rather slow, a small deposit will form, which will run out in more than 12 hours. This prolonged action by the medication will mainly involve the receptors of the district where the disease to be treated is present; only a minimal part of the therapeutic molecules will enter the bloodstream.


In the medical field, in particular orthopedic, infiltrations are defined as injections of medications (such as, for example, hyaluronic acid, local anesthetics, cortisone, etc.) or biological solutions (such as, for example, platelet growth factors or staminal cells).

In the orthopedic field, we can distinguish the following types of infiltrations:

  • articular (joint) injections
  • peri-articular injections.

In the first case, the medical solution is injected internally inside the joint, whereas in the second case the medicament is injected into an area adjacent to the joint.

The main indications for infiltrations are joint diseases (for example arthrosis or non-infective arthritis, cartilage disorders etc.) and diseases involving periarticular structures and soft tissues (bursitis, capsulitis, enthesopathies, fasciitis, fibrositis, peri-tendinitis, radicular syndromes, tendinitis, tenosynovitis, etc.)

For these purposes, the most performed injections are injections of hyaluronic acid and injections of cortisone. The widespread use of this medical practice is due both to its proved effectiveness and to the fact that positive results can be attained in a short time without practically any risks.